Ranson criteria Totally Explained

Everything about Ranson Criteria totally explained

Ranson criteria is a clinical prediction rule for predicting the severity of acute pancreatitis.

History

It was introduced in 1974.

Usage

Parameters used:
At admission:

age in years >55years
white blood cell count > 16000/mcL
blood glucose > 11 mmol/L (>200 mg/dL)
serum AST > 250 IU/L
serum LDH > 350 IU/L

After 48 hours:

Haematocrit fall > 10%

increase in BUN by 1.8 or more mmol/L (5 or more mg/dL) after IV fluid hydration

hypocalcemia (serum calcium < 2.0 mmol/L (<8.0 mg/dL))

hypoxemia (P_O₂ < 60 mmHg)

Base deficit > 4Meq/L

Estimated fluid sequestration > 6L The criteria for point assignment is that a certain breakpoint be met at anytime during that 48 hour period, so that in some situations it can be calculated shortly after admission. It is applicable to both biliary and alcoholic pancreatitis.

Interpretation

If the score >=3, severe pancreatitis likely.

If the score < 3, severe pancreatitis is unlikely Or

Score 0 to 2 : 2% mortality

Score 3 to 4 : 15% mortality

Score 5 to 6 : 40% mortality

Score 7 to 8 : 100% mortality

Mnemonic for Memorizing Ranson's Criteria

At admission: "GA LAW" (Glucose, Age, LDH, AST, WBC count)

At 48 hours: "C Hobbs" (ie. Calvin and Hobbs): (Calcium, Hematocrit, O2, BUN, Base deficit, Sequestration)Further Information

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